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Search Results for " 3 o trans p coumaroyltormentic acid "

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Cat. No.	Product Name	Target	Signaling Pathways
TN2977	3-O-trans-p-Coumaroyltormentic acid	Caspase; Antifection	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	3-O-(E)-p-coumaroyl tormentic acid may be promising lead compound for developing an effective drug for treatment of leukemia, it induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, at least in part, Topo I inhibition. 3-O-trans-p-coumaroyltormentic acid shows cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro, the IC50 values of 13.72, 14.29,14.61, 14.04 uM, respectively. 3beta-O-cis-p-Coumaroyltormentic acid, an...